I did a funky setup. I installed ST2 then put the portable version in my Dropbox. Then I deleted the contents of my Program Files\ST2 directory and linked the portable version to that folder (directory junction I think it's called in Windows). This gives me my context menu entry on right click but allows me to sync my settings with dropbox. If I wanted to, I could turn that folder into a git repo. I then did the same steps at the office... voila, synced settings. Even synced tabs which is awesome... and even more awesome is syncing unsaved tabs. I can create a new text document, put some text in there, drive to work and have that tab waiting for me. Pretty cool!
One thing I was hoping to be able to do was to create a machine specific config file. At work I use the light Soda theme since I have crazy glaring lights and the dark themes are just too much contrast. At home I switch back to the dark theme. It's easy to change, but if I could setup a machine_name_01.sublime-settings for each desktop, I'd be in heaven!