Of use sometimes is to use Ctrl-Alt-down to multi-select the next column downwards - at least it goes straight-down and you can press Escape (without typing anything!) once you've checked the alignment.
(It does jump to the left if there is a blank line, and to the right if there is a line-wrap, but still..)
Edited: Or for a block, select the block and press Ctrl-Shift-L, then Home to jump to the front of all the lines. Don't forget to press Escape, or click out, once you've checked. Edited2: Press Home twice so that you can start from the very beginning (far left).
"I'm here to save your life. But if I'm going to do that, I'll need total uninanonynymity." Me Myself & Irene.