Today, the QuickPanel works close to doing a fuzzy-search: it looks for whatever you type, but search terms have to be separated with a space.
So if I have a file called "check.php", I won't find it by looking for "cphp"; I have to type "c php" (with a space).
I'd like the QuickPanel to support true fuzzy search. I'm guessing this isn't really hard to implement, since it very closely builds on what's available now.
Many popular programs use a true fuzzy search (e.g. Launchy, Emacs).
Every time I've tried using a true fuzzy search, it's just made my life that much easier.